Towards Comprehensive Online Multidimensional Frequency Transform Separations (COMForTS)

Digital Doctoral Thesis Materials – Mark J. E. Trudgett 2014

 

This thesis represents the foundation research for a powerful new method in analytical chemistry: Comprehensive Online Multidimensional Frequency Transform Separations (COMForTS). The method was invented in response to the growing need to separate large numbers of chemicals from complex mixtures in order to better our understanding of biological processes.

Existing state-of-the-art separations were nearing their physical performance limits and required costly compromises between analytical power and analysis time. Computational modelling and laboratory experiments showed that by mathematically extracting fundamental separation information that had hitherto been lost, COMForTS can overcome these compromises, dramatically increasing the effective resolving power of multidimensional separations.

Read the thesis Abstract

 

Download the written thesis:

 

The Thesis may be downloaded in Adobe Acrobat (.pdf) format:

1.    For Windows (9.9 MB)

2.   For all other systems (35 MB)

Downloading the Complete Thesis

Option 1: Download and install the Digital Thesis Materials as supplied with the Thesis hard copy.

This option allows for the automated installation of all components and requires a total download of 4 GB, spread over seven compressed files.

This package contains the COMForTS Digital Thesis Materials as well as third party software that you may require if it is not already installed on your computer.
ALL files must be downloaded as they are parts of a single compressed (.zip) package.
Once all seven files are downloaded, the entire package can be un-compressed by un-compressing the file named “COMForTS_Digital_Thesis_Materials.zip”.  If the compressed-file extraction routines built into recent Microsoft Windows operating systems fails to un-compress these “*.zip” files, the compression utility “WinZip” (or equivalent) should be used to extract the files. A free trial version of WinZip can be found here: http://www.winzip.com

To proceed with this option, download all seven “COMForTS_Digital_Thesis_Materials.*” files from this location:
http://www.mark.trudgett.com/comforts/COMForTS_Digital_Thesis_Materials-Complete-Multipart_ZIP/

Full installation instructions are provided in the download (once un-compressed).

Option 2: Download and manually install selected components of the Digital Thesis Materials.

This option allows for the manual (package-by-package) download and installation of the necessary components that are not already installed on your computer. Each package has its own installation program but it is up to the user to decide which packages to install and to which locations. This option can save considerable download time but is NOT supported by the documentation.

COMForTS requires that you have some third party software installed on your computer (such as the Microsoft .NET Framework (version 4 or above)). Many systems will have this software already installed – in which case it is not necessary to download and/or re-install that software. Download links to the required third-party software can be found here:
http://www.mark.trudgett.com/comforts/COMForTS_Digital_Thesis_Materials-Selected_Components/Links_to_Required_Third_Party_Components.htm

To proceed with this option, download packages and files as required from this location:
http://www.mark.trudgett.com/comforts/COMForTS_Digital_Thesis_Materials-Selected_Components/

User-documentation for the COMForTS Software is provided in the (compressed) file named “COMForTS_Documentation.zip” (72 MB).

The compressed-file extraction routines built into recent Microsoft Windows operating systems are sufficient to un-compress these “*.zip” files.